August 2026 · Real-world pharma task · Verified claim

PDT THERAPY F2

Photodynamic therapy agent selection on IBM Heron r2 · ibm_kingston · 156 qubits. A pre-registered multi-logic expectation, scored PASS on raw QPC readout.

Plain English

What this task is: Choose among five therapy-only PDT drugs under three goals at once: efficacy, toxicity, and selectivity.
What we expected (locked before the run): talaporfin (Laserphyrin) must outrank padeliporfin (Tookad) on QPC multi-logic priority, because mono-efficacy says so, while a simple equal-weight average says the opposite.
What QPC computed: One coupled quantum job on ibm_kingston (Heron r2) · 18 qubits · 4096 shots · raw counts primary · public job ID below.
Headline result: PASS: talaporfin priority 0.546 > padeliporfin 0.493. The claim was verified.
What we claim: This pre-registered ranking expectation held on QPC hardware. Architecture research on a frozen public therapy-only panel.

Verdict

PASS. Expectation F2-E1 verified

QPC ranked talaporfin_sodium above padeliporfin on coupled raw multi-logic priority, against equal-weight classical on the same proxies.

PASS

Claim verdict

0.546

Talaporfin priority

0.493

Padeliporfin priority

+0.053

Margin

Why this counts as a real result

Expectation written and locked before IBM submit.
Classical methods disagree on the pair (mono-efficacy vs equal-weight).
Success = claim verified on raw coupled counts.
Architecture metrics on raw counts; resilience was diagnostic only.

Classical contrast (same proxies)

Method	Order on the pair
Mono-efficacy	talaporfin > padeliporfin
Equal-weight average	padeliporfin > talaporfin
QPC coupled raw (this job)	talaporfin > padeliporfin. PASS

Full QPC ranking (therapy-only panel)

Rank	Agent	Priority
1	verteporfin (Visudyne)	0.609
2	talaporfin_sodium (Laserphyrin)	0.546
3	padeliporfin (Tookad)	0.493
4	temoporfin (Foscan)	0.435
5	porfimer_sodium (Photofrin)	0.414

Job record

Field	Value
Backend	IBM Heron r2 · `ibm_kingston` · 156 qubits
Job ID	`da0bkvv2sl0c73bmtf2g`
Shots	4096
Geometry	5 agents × 3 logics + 3 junctions = 18 qubits
Primary metric	F2-E1 claim verdict on coupled raw priority
Label	Architecture research on frozen public therapy-only proxies. IBM Heron r2.

Setup F2 is the therapy-only panel that delivered this verified PASS: talaporfin over padeliporfin on coupled raw priority, job da0bkvv2sl0c73bmtf2g.